Morrisons in slim Xmas sales rise

first_img Morrisons in slim Xmas sales rise Wm Morrison Supermarkets posted a modest rise in Christmas sales – held back by disruption from severe weather and a tough consumer backdrop. Britain’s fourth-biggest grocer behind market leader Tesco, Asda and Sainsbury’s said sales at stores open at least a year rose one per cent excluding fuel and VAT sales tax in the six weeks to 2 January.That was down on the 1.3 per cent rise reported in its last quarter. Morrison’s said its expectations for its full financial year remained unchanged and the consumer environment was set to remain challenging amid rising taxes and public spending cuts. John Dunne Monday 10 January 2011 2:35 am whatsapp Tags: NULLcenter_img by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeMisterStoryWoman Files For Divorce After Seeing This Photo – Can You See Why?MisterStoryMoneyPailShe Was A Star, Now She Works In ScottsdaleMoneyPailTotal PastThe Ingenious Reason There Are No Mosquitoes At Disney WorldTotal PastSerendipity TimesInside Coco Chanel’s Eerily Abandoned Mansion Frozen In TimeSerendipity TimesBrake For ItThe Most Worthless Cars Ever MadeBrake For ItBetterBe20 Stunning Female AthletesBetterBeElite HeraldExperts Discover Girl Born From Two Different SpeciesElite HeraldZen HeraldThe Truth About Why ’40s Actor John Wayne Didn’t Serve In WWII Has Come To LightZen HeraldAlphaCute30 Rules That All “Hells Angels” Have To FollowAlphaCute Show Comments ▼ Read This Next’A Quiet Place Part II’ Sets Pandemic Record in Debut WeekendFamily ProofHiking Gadgets: Amazon Deals Perfect For Your Next AdventureFamily ProofYoga for Beginners: 3 Different Types of Yoga You Should TryFamily ProofIndian Spiced Vegetable Nuggets: Recipes Worth CookingFamily ProofAmazon roars for MGM’s lion, paying $8.45 billion for studio behind JamesFamily ProofThe Truth About Bottled Water – Get the Facts on Drinking Bottled WaterGayotBack on the Rails for Summer New York to New Orleans, Savannah and MiamiFamily ProofChicken Bao: Delicious Recipes Worth CookingFamily ProofCheese Crostini: Delicious Recipes Worth CookingFamily Proof whatsapp Sharelast_img read more

Chellarams Plc (CHELLA.ng) HY2018 Interim Report

first_imgChellarams Plc (CHELLA.ng) listed on the Nigerian Stock Exchange under the Industrial holding sector has released it’s 2018 interim results for the half year.For more information about Chellarams Plc (CHELLA.ng) reports, abridged reports, interim earnings results and earnings presentations, visit the Chellarams Plc (CHELLA.ng) company page on AfricanFinancials.Document: Chellarams Plc (CHELLA.ng)  2018 interim results for the half year.Company ProfileChellarams Plc is an investment holding company in Nigeria with business interests in manufacturing, retail, distribution, marketing and power generation. The company has been in operation for almost 90 years and is a leader in its field of manufacturing and distributing industrial raw materials and consumer goods. Its product portfolio ranges from industrial chemicals and machinery to ingredients for food manufacturers, frozen foods, bicycles and electronics. Chellarams Plc operates through three subsidiary companies: Chelltek Industries Limited, Dynamic Industries Limited and United Technical & Allied Services Limited. It is in a joint partnership with American Express Travel Services, Devyani International (Nigeria) Limited, Isolo Power Gen Limited and Woolworths Retail Stores Limited. The company’s head office is in Lagos, Nigeria. Chellarams Plc is listed on the Nigerian Stock Exchangelast_img read more

Rapidísimas

first_img Submit a Job Listing Rector Tampa, FL Rector Smithfield, NC Assistant/Associate Rector Washington, DC Course Director Jerusalem, Israel Rector Collierville, TN An Evening with Aliya Cycon Playing the Oud Lancaster, PA (and streaming online) July 3 @ 7 p.m. ET TryTank Experimental Lab and York St. John University of England Launch Survey to Study the Impact of Covid-19 on the Episcopal Church TryTank Experimental Lab Associate Priest for Pastoral Care New York, NY Rector Shreveport, LA In-person Retreat: Thanksgiving Trinity Retreat Center (West Cornwall, CT) Nov. 24-28 An Evening with Presiding Bishop Curry and Iconographer Kelly Latimore Episcopal Migration Ministries via Zoom June 23 @ 6 p.m. ET Priest Associate or Director of Adult Ministries Greenville, SC Rector Knoxville, TN Virtual Celebration of the Jerusalem Princess Basma Center Zoom Conversation June 19 @ 12 p.m. ET Press Release Service Cathedral Dean Boise, ID Rector Pittsburgh, PA The Church Investment Group Commends the Taskforce on the Theology of Money on its report, The Theology of Money and Investing as Doing Theology Church Investment Group Director of Music Morristown, NJ Ya no son extranjeros: Un diálogo acerca de inmigración Una conversación de Zoom June 22 @ 7 p.m. ET Bishop Diocesan Springfield, IL Episcopal Migration Ministries’ Virtual Prayer Vigil for World Refugee Day Facebook Live Prayer Vigil June 20 @ 7 p.m. ET Rector (FT or PT) Indian River, MI AddThis Sharing ButtonsShare to PrintFriendlyPrintFriendlyShare to FacebookFacebookShare to TwitterTwitterShare to EmailEmailShare to MoreAddThis The Church Pension Fund Invests $20 Million in Impact Investment Fund Designed to Preserve Workforce Housing Communities Nationwide Church Pension Group Inaugural Diocesan Feast Day Celebrating Juneteenth San Francisco, CA (and livestream) June 19 @ 2 p.m. PT Curate (Associate & Priest-in-Charge) Traverse City, MI El 14 de julio la Iglesia de Inglaterra (Anglicana) hizo historia al aprobar la consagración de mujeres al episcopado después de una lucha que duró más de 30 años. La moción fue aprobada por el Sínodo General el grupo directivo de la iglesia formado por tres cámaras con representantes de obispos, sacerdotes y laicos de las diócesis de la iglesia. La votación fue la siguiente: 351 votos a favor, 72 en contra y 10 abstenciones. La moción ahora tendrá que pasar al Parlamento para su discusión que la remitirá a la reina Isabel II para su firma. La Iglesia de Inglaterra es la denominación más numerosa de Inglaterra y forma parte de la Comunión Anglicana, presente en 160 países.Con diversos actos la comunidad cubana del exilio rindió tributo el 13 de julio a las víctimas del hundimiento del Remolcador “13 de Marzo” en el que perecieron hace 20 años 37 personas en su mayoría niños y mujeres. El grupo quería escapar de Cuba y fue atacado con fuertes chorros de agua de otra embarcación que hundió el remolcador. Liderado por el activista José Raúl Sánchez una flotilla de embarcaciones llegó hasta el límite de las aguas jurisdiccionales y lanzó cientos de luces y cohetes de fuegos artificiales que fueron vistos desde La Habana. El hundimiento del remolcador es uno de los actos más crueles del régimen de La Habana, dijo Sánchez. Hasta el momento no se ha enjuiciado a nadie.El conflicto armado en la Faja de Gaza entre Israel y Palestina ha ido en aumento y ya se cuentan 195 víctimas palestinas. Por el momento no se vislumbra un cese al fuego.  Cientos de familias de Gaza han tenido que abandonar sus hogares para protegerse de la artillería israelí. Todo empezó cuando hace varias semanas tres jóvenes judíos fueron muertos por miembros de Hamás. Organizaciones internacionales han tratado de mediar sin resultado alguno. Hay temor de que el conflicto se convierta en una guerra civil.Después de la terminación de la Copa Mundial en la que Alemania resultó ganadora en una reñida justa con Argentina, cientos de manifestantes realizaron actos de violencia callejera alrededor del Obelisco, monumento emblemático central de la ciudad de Buenos Aires. La policía hizo varios arrestos. Algo similar ha ocurrido en Brasil.Observadores políticos afirman que Brasil tiene a la vista una seria crisis económica por los enormes gastos que se realizaron como preparación para los juegos. Citan, por ejemplo, el enorme estadio que se fabricó en Manaus una ciudad bastante pequeña que nunca podrá llenar el estadio. Manaus está situada en la confluencia de los ríos Negro y Solimoes en la parte norte de Brasil.Kenneth Johnson, un pastor evangélico de 67 años fue baleado el 10 de julio en una pequeña tienda en Liberty City una sección de Miami donde residen muchas familias afro-americanas. El móvil del asesinato realizado por dos jóvenes de la comunidad fue para robarle una cadena que prendía de su cuello y que ellos no sabían que era falsa. Johnson era pastor de la iglesia Power Faith and Deliverance y era muy querido y respetado en la comunidad.La situación de cientos de niños sin sus padres que han llegado hasta la frontera sur de Estados Unidos sigue sin resolverse. El gobierno norte-americano ha dicho que los niños serán repatriados pero mientras tanto necesitan alimentación, ropas y cuidado médico. Los niños y muchas de las madres que los acompañan proceden de Guatemala, Honduras y El Salvador y han llegado hasta aquí en el techo de un tren de carga apodado “La Bestia” donde abundan el peligro y los abusos de todas clases. Esta situación ha sido catalogada como una “crisis humanitaria”, la más seria en muchos años. El grito de auxilio ha llegado hasta Roma donde el papa Francisco ha enviado al cardenal Pietro Parolín, secretario de Estado del Vaticano, para que trate de ayudar en la crisis.“Estos niños deben ser bienvenidos y protegidos”, dijo el papa Francisco. Katharine Jefferts Schori, obispa presidenta de la Iglesia Episcopal, ha pedido que el gobierno de Estados Unidos que actúe con justicia y generosidad ante tanto sufrimiento humano.Durante la era de Hitler en Alemania se buscó a una niña que fuera bonita y “completamente blanca” con el fin de exaltar la raza aria. La foto de la niña fue publicada en la portada de una revista de circulación nacional. Ahora mediante pruebas científicas se ha determinado que la niña era judía y su nombre es Hessy Taft, que logró salvarse de los campos de concentración, vive en los Estados Unidos y tiene 80 años.REFRAN. No todo lo que brilla es oro. Rector Martinsville, VA Associate Rector Columbus, GA Priest-in-Charge Lebanon, OH Rector Bath, NC Associate Rector for Family Ministries Anchorage, AK Missioner for Disaster Resilience Sacramento, CA Rector Belleville, IL New Berrigan Book With Episcopal Roots Cascade Books Curate Diocese of Nebraska Rector Washington, DC Episcopal Charities of the Diocese of New York Hires Reverend Kevin W. VanHook, II as Executive Director Episcopal Charities of the Diocese of New York Rapidísimas Youth Minister Lorton, VA Remember Holy Land Christians on Jerusalem Sunday, June 20 American Friends of the Episcopal Diocese of Jerusalem Episcopal Church releases new prayer book translations into Spanish and French, solicits feedback Episcopal Church Office of Public Affairs Por Onell A. SotoPosted Jul 16, 2014 Family Ministry Coordinator Baton Rouge, LA Submit a Press Release Director of Administration & Finance Atlanta, GA Seminary of the Southwest announces appointment of two new full time faculty members Seminary of the Southwest Featured Events Rector Albany, NY Canon for Family Ministry Jackson, MS Rector and Chaplain Eugene, OR Featured Jobs & Calls Join the Episcopal Diocese of Texas in Celebrating the Pauli Murray Feast Online Worship Service June 27 This Summer’s Anti-Racism Training Online Course (Diocese of New Jersey) June 18-July 16 Rector Hopkinsville, KY Assistant/Associate Priest Scottsdale, AZ Submit an Event Listing Rector/Priest in Charge (PT) Lisbon, ME Assistant/Associate Rector Morristown, NJlast_img read more

What next for this well-known former Reapit sales manager?

first_imgHome » News » What next for this well-known former Reapit sales manager? previous nextProptechWhat next for this well-known former Reapit sales manager?Peter Fenwick has today revealed that he is to become a proptech consultat to sales and letting agents ‘confused’ about how best to utilise tech.Nigel Lewis24th September 20180946 Views Former Reapit sales manager Peter Fenwick has revealed that he is to launch himself as an independent proptech consultant.Peter, who for nearly a decade lead the sales team at the property software supplier, on Friday revealed that he had finished his last day at the company and that he would be launching his new business this week.His departure was part of a major shake-up at Reapit in July during which its colourful sales director Simon Whale also left the company.“I’d like to thank my colleagues past and present for their support over the past nine years,” says Peter.“I’m really proud of what we achieved during that period and I wish all of you the best of luck for the future.”ProptechPeter, who has worked in the property industry both on the agent and technology side, says his new venture will offer estate agents expert independent advice to help those who are “confused by the myriad of information and mis-information out there about proptech”.“There are a lot of senior managers or business owners out there who have a strong suspicion that their company is wasting money on tech with no measurable return on investment,” he says.Peter, who is also a keen runner and charity fundraiser, started out as a trainee negotiator at Halifax Property Services in South London before working for several other agents including YourMove. He then joined Vebra in 2005 and Reapit in 2009.He also advises Sevenoaks-based buildings surveys tech firm Spatial Dimensions.Peter Fenwick Reapit Simon Whale. vebra September 24, 2018Nigel LewisWhat’s your opinion? Cancel replyYou must be logged in to post a comment.Please note: This is a site for professional discussion. Comments will carry your full name and company.This site uses Akismet to reduce spam. Learn how your comment data is processed.Related articles BREAKING: Evictions paperwork must now include ‘breathing space’ scheme details30th April 2021 City dwellers most satisfied with where they live30th April 2021 Hong Kong remains most expensive city to rent with London in 4th place30th April 2021last_img read more

CO Collection Specialist

first_img Salary Not Specified JH at WhiteMarsh Special knowledge, skills, andabilities:Able to operate basicoffice equipment, e.g. photo copier, fax machine, scanner, PC,telephone, etc. Technical qualifications or specializedcertifications:Knowledge of medicalterminology, CPT codes and diagnosis coding required.Any specificphysical requirements for the job:Able to sit in a normalseated position for extended periods of time.Able to reach by extendinghand(s) or arm(s) in any direction.Finger dexterity required,able to manipulate objects with fingers rather than entire hand(s)or arm(s), e.g., use of computer keyboard.Able to communicate usingthe spoken and written word.Able to see within normalparameters and to hear within normal range.Able to moveabout.Able to lift minimumweight, 10 lbs.ClassifiedTitle:Collection SpecialistWorking Title: CO CollectionSpecialistRole/Level/Range: ATO 40/E/02/OC Starting Salary Range:$13.36 – $18.41/hrEmployee group: Full Time Schedule: M-F 8 to 4:30pm Exempt Status: Non-ExemptLocation: 16-MD:JH at White Marsh Department name: 10003029-SOM Oto Production Unit BillingPersonnel area: School of MedicineThe successful candidate(s) for this position will be subject toa pre-employment background check.If you are interested in applying for employment with The JohnsHopkins University and require special assistance or accommodationduring any part of the pre-employment process, please contact theHR Business Services Office [email protected] For TTYusers, call via Maryland Relay or dial 711.The following additional provisions may apply dependingon which campus you will work. Your recruiter will adviseaccordingly.During the Influenza (“the flu”) season, as a condition ofemployment, The Johns Hopkins Institutions require all employeeswho provide ongoing services to patients or work in patient care orclinical care areas to have an annual influenza vaccination orpossess an approved medical or religious exception. Failure to meetthis requirement may result in termination of employment.The pre-employment physical for positions in clinical areas,laboratories, working with research subjects, or involvingcommunity contact requires documentation of immune status againstRubella (German measles), Rubeola (Measles), Mumps, Varicella(chickenpox), Hepatitis B and documentation of having received theTdap (Tetanus, diphtheria, pertussis) vaccination. This may includedocumentation of having two (2) MMR vaccines; two (2) Varicellavaccines; or antibody status to these diseases from laboratorytesting. Blood tests for immunities to these diseases areordinarily included in the pre-employment physical exam except forthose employees who provide results of blood tests or immunizationdocumentation from their own health care providers. Anyvaccinations required for these diseases will be given at no costin our Occupational Health office.Equal Opportunity EmployerNote: Job Postings are updated daily and remain online untilfilled.EEO is the LawLearn more:https://www.eeoc.gov/sites/default/files/migrated_files/employers/poster_screen_reader_optimized.pdf Save CO Collection Specialist Business & Administrative Affairs Not specified Full Time jobs in Baltimore LinkedIn CO Collection Specialist Generalsummary/purpose:The Collection Specialist will be responsible for the collection ofunpaid third-party claims and appeals, using various applicationsof JHM and JHU/ PBS billing applications. Works with the payers toresolve issues and facilitate prompt payment of claims. Follow-upwith insurance companies to collect outstanding accounts for whichpayment has not been received in response to the claims submissionprocess, either electronically or by paper. The Specialist will beassigned all payor groups of outstanding patient accounts. Variousmethods of follow-up will be used including all JHU/ PBS BillingApplications. The Specialist must have expertise in insurancefollow-up processing and be knowledgeable in CPT and diagnosiscoding as well as have an understanding of the JHOC registrationprocess and be able to recognize and resolve incorrect demographicand insurance registration. The Specialist must have anunderstanding of claims submission requirements for all payors toexpedite payments as well as knowledge of appeals and rejectionsprocessing. This position requires excellent communicationskills.Note: This position is noteligible for visa sponsorship.Specific duties& responsibilities:Uses A/R follow-up systemsand reports to identify unpaid claims forcollection/appeal.Gathers and verifies allinformation required to produce a clean claim including specialbilling procedures that may be defined by a payer orcontract.Review and update patientregistration information (demographic and insurance) asneeded.Applies appropriatediscounts / courtesies based on department policy.Prepares delinquentaccounts for transfer to self-pay collection unit according to thefollow-up matrix.Prints and mails claimforms and statements according to the follow-up matrix.Retrieves supportingdocuments (medical reports, authorizations, etc) as needed andsubmits to third party payers.Appeals reflected claimsand claims with low reimbursement.Confirm credit balancesand gathers necessary documentation for processingrefund.Identifies insuranceissues of primary vs. secondary insurance, coordination of benefitseligibility and any other issue causing non-payment ofclaims.Contacts the payors orpatient as appropriate for corrective action to resolve the issueand receive payment of claims.Monitor invoice activityuntil problem is resolved.Process daily mail, editsreports, file or pull EOB batches.Identifies and informs thesupervisor / Production Unit Manager of issues or problemsassociated with non-payment of claims.TechnicalKnowledge:Comprehensive knowledgeand compliance of HIPAA rules and regulations in the disseminationof patient Protected Health Information (PHI).Working knowledge of JHU/PBS Billing Applications.Utilize online resourcesto facilitate efficient claims processing.Professional &Personal Development:Participate in on-goingeducational activities.Keep current of industrychanges by reading assigned material on work relatedtopics.Complete three days oftraining annually. Maryland, United States Share Apply(This will open in a new window from which you will be automatically redirected to an external site after 5 seconds) You need to sign in or create an account to save Salary Not Specified Maryland, United States Johns Hopkins University Computer Services & Information Technology Not specified Full Time jobs in Baltimore Maryland, United States CO Collection Specialist Minimum qualifications(mandatory):HS Diploma/GEDrequired.One (1) year medicalbilling experience or demonstrated knowledge of medical billingconcepts, preferably Pro Fee Billing.Additional education maysubstitute for required experience, to the extent permitted by theJHU equivalency formula.Excellent interpersonal,communication and customer service skills required.Ability to use variousbilling and patient information, computer systems, EPIC preferred,but not required.Knowledge of various payerprocessing and submission guidelines required.Any other duties asassigned.Additional educationbeyond minimum experience qualifications may substitute forrequired experience to the extent permitted by the JHU equivalencyformula.Able to operate basicoffice equipment, e.g. photo copier, fax machine, scanner, PC,telephone, etc. Save CO Collection Specialist Johns Hopkins University CO Collection Specialist The successful candidate(s) for this position will be subject to apre-employment background check.If you are interested in applying for employment with The JohnsHopkins University and require special assistance or accommodationduring any part of the pre-employment process, please contact theHR Business Services Office at [email protected] For TTYusers, call via Maryland Relay or dial 711.The following additional provisions may apply depending on whichcampus you will work. Your recruiter will adviseaccordingly.During the Influenza (“the flu”) season, as a condition ofemployment, The Johns Hopkins Institutions require all employeeswho provide ongoing services to patients or work in patient care orclinical care areas to have an annual influenza vaccination orpossess an approved medical or religious exception. Failure to meetthis requirement may result in termination of employment.The pre-employment physical for positions in clinical areas,laboratories, working with research subjects, or involvingcommunity contact requires documentation of immune status againstRubella (German measles), Rubeola (Measles), Mumps, Varicella(chickenpox), Hepatitis B and documentation of having received theTdap (Tetanus, diphtheria, pertussis) vaccination. This may includedocumentation of having two (2) MMR vaccines; two (2) Varicellavaccines; or antibody status to these diseases from laboratorytesting. Blood tests for immunities to these diseases areordinarily included in the pre-employment physical exam except forthose employees who provide results of blood tests or immunizationdocumentation from their own health care providers. Anyvaccinations required for these diseases will be given at no costin our Occupational Health office.Equal Opportunity EmployerNote: Job Postings are updated daily and remain online untilfilled.EEO is the LawLearn more:https://www1.eeoc.gov/employers/upload/eeoc_self_print_poster.pdfImportant legal informationhttp://hrnt.jhu.edu/legal.cfm Johns Hopkins University Similar jobs Financial Affairs Not specified Full Time jobs in Baltimore Twitter You need to sign in or create an account to save You need to sign in or create an account to save More searches like this Save CO Collection Specialist Facebook Administrative Not specified Full Time jobs in Baltimore Salary Not Specifiedlast_img read more

IDP Statement on Mayor Pete Buttigieg’s Announcement

first_imgJohn Zody, Chairman of the Indiana Democratic Party, released the following statement after South Bend Mayor Pete Buttigieg announced his intentions to run for Chair of the Democratic National Committee.“November’s election made one point very clear – the Midwest and the issues important to this region should never be ignored. More attention must be made to growing wages for the hardworking middle-class, investing in training programs that are needed to bridge a skills gap, and bringing a Hoosier Common Sense approach to solving important issues like equality. With investments in things like community development, job creation, and infrastructure during his time as Mayor of South Bend, Pete Buttigieg has the capability of bringing a much-needed Midwest voice to the Democratic Party that will resonate across the country. Pete is a young and dynamic talent that we need at the top of our party, and I am happy to support a Hoosier for DNC Chair. I encourage my fellow DNC members to get to know Mayor Pete Buttigieg over the next seven weeks.”FacebookTwitterCopy LinkEmailSharelast_img read more

Education in the Courts: Vergara v. California

first_imgOn March 4, Los Angeles County Superior Court Judge Rolf Treu rejected a motion to dismiss the Vergara v. California case and continue the state’s education trial where nine students are challenging the laws over teacher job protection. The suit, filed on behalf of Beatriz Vergara, a Los Angeles high school student, and eight other public school students, claims that the law protects poor-performing teachers assigned to working with low-income, minority children. The trial has resumed and will likely last for several months. Dean James Ryan answered some questions about the case and its relevance to education today. Read Full Storylast_img

The ruse of ‘fake news’

first_img Town halls, without the screaming or scripting Catching criminals through their relatives’ DNA Panelists ponder the future of journalism in a click-happy, unsourced world Fake news is giving reality a run for its money Related The Boston Globe To ensure that false content isn’t amplified across platforms, the study called on companies to do a better job of policing the use of software bots that control fake accounts — studies have estimated that anywhere from 9 to 15 percent of active Twitter accounts are bots, and that there may be as many as 60 million bots on Facebook — and identify and remove false content.“Generally, the platforms should avoid accidentally amplifying low-quality content when detecting what is trending,” Lazer said. “That seems like a no-brainer.”Though major companies like Google, Facebook, and Twitter have taken steps to counteract fake news, with Twitter moving to block accounts linked to Russian misinformation and Facebook announcing plans to shift its algorithm to account for “quality” in its content curation, the authors said the platforms have not provided enough detail about those steps for the research community to evaluate them properly.The authors outline two primary strategies to stem the flow and influence of fake news: empowering individuals to better evaluate the credibility of news and news sources they encounter, and making structural changes to prevent exposure to fake news in the first place.Though neither goal will be easy, Baum and Lazer admit, both could, over time, help restore citizen trust and credibility in news and information sources.“Our call here is to promote interdisciplinary research with the objective of reducing the spread of fake news and of addressing the underlying pathologies it has revealed,” the authors wrote. “More broadly, we must answer a fundamental question: How can we create a news ecosystem and culture that values and promotes truth?”This research was supported with funding from the Shorenstein Center at the Harvard Kennedy School and the NULab for Texts, Maps, and Networks at Northeastern University. Finding genetic needles in database haystacks As Americans increasingly turn to social media as their primary source for news and information, the dangers posed by the phenomenon of “fake news” are growing.Reports of foreign influence on the 2016 U.S. presidential election are only the most high-profile example of how the infusion of misinformation into social media can influence democratic institutions. Determining how to measure and counter untruths in the digital age, however, is still in its early stages.In a recent study described in the journal Science, lead authors Matthew Baum, the Marvin Kalb Professor of Global Communications, David Lazer, a professor at Northeastern University and an associate of the Harvard Institute for Quantitative Social Science, and more than a dozen co-authors argue that a multidisciplinary effort is needed to understand better how the internet spreads content and how readers process the news and information they consume. Such broad-based efforts are necessary, the authors said, “to reduce the spread of fake news and to address the underlying pathologies it has revealed.”“There needs to be some regular auditing of what the platforms are doing and how much this information is spreading,” Lazer added, “because there is a collective interest in the quality of the information ecosystem that we all live in.”In addition to Baum and Lazer, the paper was co-authored by Yochai Benkler, Adam J. Berinsky, Kelly M. Greenhill, Filippo Menczer, Miriam J. Metzger, Brendan Nyhan, Gordon Pennycook, David Rothschild, Michael Schudson, Steven A. Sloman, Cass R. Sunstein, Emily A. Thorson, Duncan J. Watts, and Jonathan L. Zittrain.The rise of fake news, the authors said, can be chalked up in part to two opposing trends in American society. Recent Gallup polls have found a growing mistrust of U.S. media, and studies have also said that nearly half of Americans “often or sometimes” get their news from social media, with Facebook being the dominant source.While those platforms have enabled new information sources and voices to emerge, they have also made it far easier for people to engage only with homogeneous social networks and take in only information that affirms their own views, thereby exacerbating the ideological divides in the country.“The internet has reduced many [previously enforced] constraints on dissemination of news. This allows outlets that do not embody these norms to compete online with those that do on a relatively more equal footing than was possible offline,” the authors argued in the paper. “This has contributed to the abandonment of traditional news sources that had long enjoyed high levels of public trust and credibility.”In some cases, Baum and Lazer said, social networks have unwittingly become complicit in amplifying fake news.As an example, they point to Twitter’s trending mechanism. When the platform notices a surge in tweets about a particular topic — such as a celebrity’s birthday or an approaching nor’easter — Twitter may list the topic as trending. But studies have repeatedly shown that the process can be manipulated. In one case journalists found that for as little as $200, a company in Saudi Arabia would deploy an army of bots to make any hashtag trend for a few hours.last_img read more

Fears arise that new federal fetal-tissue restrictions will hobble a ‘workhorse’ of research

first_img Breakthrough research shows that stem cell genes can be edited in living systems Discovery of a novel reprogramming method of adult cells could shift stem cell research Researchers create embryonic stem cells without embryo Editing genes at the source  DALEY: The scientific community has already spent, arguably, billions of dollars seeking alternatives. Because, even though it’s permissible today, obtaining human fetal tissues is challenging and already burdened by tremendous regulatory oversight. If we had better alternatives, we’d use them.So I’m somewhat skeptical that $20 million will do anything more than give political cover to the new restrictions. GAZETTE: Are some scientists concerned that this policy politicizes science?DALEY: Let me answer that as diplomatically as possible. As a practicing scientist working in the field of cancer and stem cell biology, having benefitted and learned a tremendous amount from the opportunity to use fetal tissues, I don’t believe that these restrictions are based on any plausible scientific rationale.Scientists concluded long ago and continue to argue for the central and essential importance of fetal tissue research in advancing medical knowledge and improving human health.center_img DALEY: My research over the last two decades has included deriving continuous cell lines from human embryos, creating so-called embryonic stem cell lines.These embryonic stem cell lines can grow forever in a petri dish, and they’ve been enormously powerful tools for research and the first therapies derived from embryonic stem cells are being tested in the clinic. However, they alone aren’t an adequate substitute for fetal tissue. We need to compare and contrast the results of our experiments in the petri dish with what actually happens during human fetal development, and for that we need fetal tissue.In our own work, our goal has been to derive blood, blood lineages, and blood stem cells from embryonic and pluripotent stem cells. The blood stem cell is the vehicle we use for curative bone marrow transplants for leukemia and various genetic blood diseases like immune deficiency. We’ve had some success in deriving facsimiles of bona fide human blood stem cells, but we only know that because we have access to actual blood stem cells that come from fetal tissue.In addition, we can literally take fetal tissues, a fetal hematopoietic (blood-production) system, and transplant it into a mouse. Fetal tissue research has entailed transplanting human fetal liver, fetal thymus, and fetal bone marrow into mice, creating humanized murineavatars of the human lymphoid and hematopoietic system.That has provided a powerful model for testing HIV infection, for establishing strategies to block HIV infection, and to create vaccines against HIV. It’s also, in our own experiences, given us vehicles to test whether we have succeeded in establishing human hematopoietic stem cells from these various pluripotent stem cell sources.GAZETTE: People may feel squeamish about blending human and mouse tissues. Since you can’t experiment on healthy humans, how many alternatives are there? DALEY: It’s the best we have.We’re not creating human organs in a mouse. These are pieces of tissue — in some cases microscopic clusters of cells — that come from human fetal liver, or human fetal thymus, or human fetal bone marrow. They get transplanted into an immune-deficient mouse — immune-deficient so it doesn’t reject the human cells. And it allows us to establish a human blood system in a mouse.Transplanting human tissues and cells into immune-deficient mice has been practiced for decades and it’s been enormously powerful for cancer research, for gene therapy research, for HIV research. There’s really no good alternative.If we had good alternatives, we’d use them.GAZETTE: Part of the challenge for any mouse research comes once you get results and seek to understand whether those results translate to a human. By using these embedded human tissues, does that begin to give you the answer while still working on a mouse?DALEY: That’s right. In our work on blood development, we can study mouse hematopoiesis, but that teaches us about blood in the mouse, and there are key differences between mouse blood and human blood. So the next-best approach is to establish the human blood-forming system in the mouse.That then allows us to study, manipulate experimentally and therapeutically human blood in a way that doesn’t involve testing directly on human patients. It’s safer and allows for a broader range of experiments.GAZETTE: We have just have a couple of minutes left, but I did want to get to some of the details of the administration’s plan. I wanted to touch on the idea that, outside of banned research at NIH and UCSF, grants for this work will be reviewed by a new ethical advisory board. What your thoughts are on that?DALEY: My concern about setting up another level of regulatory review by these ethical review boards within the NIH is that it is redundant, since we are already subject to ethical review at our home institutions.I worry that an additional review within NIH would introduce delays and impose standards that are potentially more restrictive.We’ve seen this happen before. When the NIH approved an expanded review of embryonic stem cell studies, it established its own internal review process that was cumbersome and introduced delays into the system. Ultimately, a lot of experiments that were highly worthy never got done.We saw the same issue when the NIH imposed a special review on so called human-animal “chimera” experiments. The policy produced a delay of months and even years in some cases. I’d have to go back to review, but I’m not even sure any applications were ultimately ever approved.So I worry that the new administration policy is an attempt to offer the appearance of a compromise when in fact it’s another means of simply obstructing the research.GAZETTE: In announcing the restrictions, HHS pointed to its announcement last December to spend $20 million on alternatives to fetal tissue research. Is that a meaningful amount when looking for alternatives to this kind of research? Earlier this month, the U.S. Department of Health and Human Services (HHS) announced new restrictions on government-funded research conducted on fetal tissue.The department said it would end such research conducted at the National Institutes of Health and terminate a $2 million contract it had for similar work conducted at the University of California at San Francisco. NIH-funded research done at other institutions, including Harvard, will be allowed to continue until current grants run out. After that, projects seeking funding will be evaluated by a new ethics advisory board before approval.In its statement, HHS also highlighted plans that were announced in December to spend $20 million to search for alternatives to the use of fetal tissue from elective abortions in medical research.And the agency noted: “Promoting the dignity of human life from conception to natural death is one of the very top priorities of President Trump’s administration.”Harvard Medical School Dean George Daley spoke with the Gazette about the importance of fetal tissue research, which has been used in creating and testing vaccines, the emerging field of gene therapy, and in research to better understand conditions from HIV to Zika virus.Q&AGeorge DaleyGAZETTE: When we talk about fetal tissue research, what exactly are we talking about?DALEY: It is research on the tissues that result from either elective or spontaneous abortions.The right of a woman to control her own reproductive fate has been established in U.S. law for decades and that has meant that physicians and scientists have had access to material that, after an elective procedure, would have otherwise been discarded as medical waste.That tissue has been used in research and therapy for many decades, to the great advantage of patients everywhere.GAZETTE: How significant has the use of this material been?DALEY: The use of fetal tissues has contributed to the development of numerous vaccines that have saved countless lives and prevented a huge burden of disease, especially in childhood, as well as various therapeutic strategies for diseases affecting adults.The robust growth properties of fetal cells have allowed scientists to create cell lines that are the manufacturing platform for vaccines. After many decades of experience, we know the cell lines that grow from early fetuses are easier to grow and more plastic in their properties, and consequently have lent themselves to very vigorous establishment and use in laboratories.A vast number of gene-therapy strategies depend on producing viral vectors in fetal cell cultures. Gene therapy is now widely employed and is curing children with devastating conditions like immune deficiency and, soon, sickle cell anemia.There also has been a limited — but promising — use of fetal tissues for the treatment of certain conditions like Parkinson’s disease. Beyond that, the ability to culture fetal tissues has contributed to insights into conditions that affect human development, like the influence of viruses on the developing brain. That occurred most notably and most recently with the Zika virus, which has been associated with microcephaly and brain developmental defects. The fundamental insights into that disease were dependent on access to fetal tissues.In my own research, we seek to understand the early development of blood as a tissue. Similar strategies apply for scientists who are interested in the development of other organs, including the heart, the lungs, the pancreas, and the brain.Access to fetal tissues has provided enormous insights that cannot be supplanted or substituted by model systems. We have learned much from studying blood development in the mouse, but ultimately we need to understand how the human blood system develops, and for that, access to fetal tissues is invaluable. GAZETTE: You mentioned cell lines from fetal tissue as important research tools. What is a cell line and why is it important to scientific research?DALEY: When we establish a colony of cells in a petri dish, growing in a nutrient liquid, those cells will divide: One cell becomes two; two become four; four become eight; and before you know it, you’ve got millions of cells that can be studied.GAZETTE: And they’re for a specific type of tissue?DALEY: That’s right. We typically establish a population of cells in a petri dish that are all the same cell type. One might cultivate a petri dish full of liver cells or brain cells or muscle cells or blood cells and those become enormously powerful tools for studying tissue development.And, at some low frequency, some of these cells will become immortal.Cells in a petri dish typically have a limited lifespan. Fetal cells tend to have a much-prolonged lifespan and occasionally will convert into an immortal cell type. That will then be considered a “cell line,” a lineage of cells deriving from its original forebears, but that can be perpetuated forever in culture.Many of these lines derived from fetal tissues have become workhorses of research around the globe. They’re employed in developing vaccines and have become vehicles for generating and manufacturing gene-therapy products. One can see how vitally important they are to cell biology and to biomedical research. GAZETTE: Some people have asked, “Aren’t stem cells a viable replacement for fetal tissue?” “Many of these lines derived from fetal tissues have become workhorses of research around the globe.” Relatedlast_img read more

Warren County Sporting Goods Store Enhancing COVID-19 Precautions

first_imgShare:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to email this to a friend (Opens in new window) Image via talltalesoutdoor.com.RUSSELL – A outdoors store in Warren County is implementing new COVID-19 precautions as new cases of the virus continue to increase in the area.Tall Tales Sporting Goods in Russell is moving to curbside pickup for all non-firearm purchases starting Saturday.They are urging customers to order online, choosing the in-store pick-up option.Once the order is ready, the store will call and let the customer know. When customers arrive, they are asked to say in their vehicles and staff will bring the order out to them. Additionally, the stores is not selling hunting or fishing licenses for the time being and all firearm purchases will need to be made on an appointment basis.“Customers can order online and choose in store pick-up,” said staff in a post on their website. “We will call you once we have processed your order and schedule an appointment for pick up and firearm transfer.”They say only one person will be allowed in the store by appointment.“You will not be allowed to browse or shop in the store during this time,” they furthered. “You must be wearing a face covering for your appointment. No mask, no entry, no exceptions.”last_img read more